[Sin is] an energy, an obsession, an allergic reaction to God’s law, an irrational anti-God syndrome in our spiritual system that drives us to exalt ourselves and steels our hearts against devotion and obedience to our Maker. Pride, ingratitude, and self-gratification are its basic expressions, leading sometimes to antisocial behavior and always, even in the nicest and most honorable people, to a lack of love for God at the motivational level.

JI Packer, A Passion for Holiness 

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